Teutopolis, "City of the Teutons", or Germans, was established in 1839 along the National Road, now U.S. Route 40. It is the only town in the United States with this name.
Clemens Uptmor from the Duchy of Oldenburg, and Kingdom of Hanover, Germany, came to the United States in 1834 along with his brother Herman H. Uptmor and a few neighbors. They settled first in Cincinnati, then the gateway to the west for German Catholics.